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1.
Photodiagnosis Photodyn Ther ; 41: 103239, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36535599

RESUMO

BACKGROUND: The aim of this study was to evaluate efficacy of violet LED light for the bleaching treatment of primary incisors darkened by trauma. METHODS: Twenty deciduous incisors with color change were selected, divided into two groups: control - no bleaching protocol was applied, and VL- treated with violet LED. The change color analysis was taken in each tooth, by spectrophotometer. In three different time: baseline - before treatment, after 4 treatment sessions and after 8 treatment sessions. RESULTS: The color change data were analyzed using ANOVA and a post- hoc Tukey tests (α=0.05). After 4 and 8 sessions no differences were observed between the groups (p<0.05). CONCLUSIONS: Thus, it can be concluded that violet LED light was not effective in bleaching primary incisors darkened by trauma after 8 sessions.


Assuntos
Fotoquimioterapia , Clareadores Dentários , Clareamento Dental , Peróxido de Hidrogênio , Incisivo , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes , Cor
2.
Rev. Odontol. Araçatuba (Impr.) ; 43(1): 41-44, jan.-abr. 2022. ilus
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1361662

RESUMO

Background: Glanzmann thrombasthenia (GT) is a rare autosomal recessive disorder characterized by platelet function impairment. Considering that the oral cavity is highly vascularized and performing some local hemostatic maneuvers may be difficult, GT patients are at high risk for hemorrhage related to invasive oral procedures. This study aimed to present an alternative method for periodontal surgery in a young GT patient. Case Report: A 15-year-old female GT patient with a recent history of excessive bleeding following dental surgeries was referred to a public dental center, presenting gingival hyperplasia. The procedure was performed using a high-power laser (HPL), and except for local anesthesia with epinephrine, no further hemostatic agent was necessary. Conclusion: According to the case, the HPL seems to be an efficient tool for preventing perioperative bleeding in GT patients submitted to minor oral surgeries(AU)


Introdução: A trombastenia de Glanzmann (TG) é uma doença autossômica recessiva rara caracterizada por comprometimento da função plaquetária. Tendo em vista que a cavidade oral é altamente vascularizada e a realização de algumas manobras hemostáticas locais pode ser difícil, pacientes com TG apresentam alto risco de hemorragia relacionada a procedimentos orais invasivos. Este artigo teve como objetivo apresentar uma técnica alternativa para cirurgia periodontal em um paciente jovem com TG. Relato de Caso: Paciente com TG, sexo feminino, 15 anos, com história recente de sangramento excessivo relacionado a cirurgias odontológicas prévias, foi encaminhada a um centro odontológico público apresentando hiperplasia gengival. O procedimento de remoção foi realizado com laser de alta potência e, com exceção da anestesia local com epinefrina, nenhum outro agente hemostático foi necessário. Conclusão: De acordo com o caso, o laser de alta potência parece ser uma ferramenta eficiente na prevenção de sangramento perioperatório em pacientes com TG submetidos a pequenas cirurgias orais(AU)


Assuntos
Humanos , Feminino , Adolescente , Cirurgia Bucal , Trombastenia , Transtornos da Coagulação Sanguínea , Terapia a Laser , Lasers Semicondutores , Hiperplasia Gengival
4.
Semin Thromb Hemost ; 47(6): 702-708, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33971681

RESUMO

The objective of this systematic review is to assess the risk of postoperative bleeding in oral surgery for implant placement in individuals taking antithrombotics (i.e., anticoagulants and/or antiplatelet agents). A literature search was performed in PubMed (MEDLINE), Web of Science, Scopus, and EMBASE databases for articles published until August 2020, with no date restriction, and manually completed. We included prospective clinical studies that provided information regarding the presence of an experimental group (i.e., implant placement), a control group (patients not under treatment with antithrombotics), and a well-established protocol for evaluating bleeding. Meta-analysis determined the risk of bleeding during the placement of implants in antithrombotic-treated patients. Of the 756 potentially eligible articles, 5 were included in the analysis with 4 ranked as high and 1 as medium quality. Antithrombotic treatment comprised the following drug classes: (1) anticoagulants: vitamin K antagonists, (2) nonvitamin K antagonist oral anticoagulants, (3) low-molecular-weight heparin, and (4) antiplatelet agents (not specified). The results suggest that the risk of bleeding is not substantially higher in antithrombotic-treated patients (odds ratio = 2.19; 95% confidence interval: 0.88-5.44, p = 0.09) compared with nontreated patients. This systematic review suggests that the absolute risk is low and there is no need to discontinue or alter the dose of the antithrombotic treatment for implant placement surgery.


Assuntos
Anticoagulantes , Fibrinolíticos , Anticoagulantes/efeitos adversos , Fibrinolíticos/efeitos adversos , Heparina de Baixo Peso Molecular , Humanos , Hemorragia Pós-Operatória , Estudos Prospectivos
5.
Photodiagnosis Photodyn Ther ; 34: 102247, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33711533

RESUMO

Osteoradionecrosis (ORN) is considered one of the most severe complications of radiotherapy (RT). Treatment modalities for ORN may vary considerably, including conservative or surgical procedures. Recently, alternative managements such as the combination of photobiomodulation therapy (PBMT) and antimicrobial photodynamic therapy (aPDT) have also yielded promising results in patients presenting ORN or delayed healing post-RT. Herein, it is reported a case of ORN manifested as an oral fistula on the mandibular alveolar mucosa in which a combination of PBMT and aPDT was used every 15 days for six weeks. A laser device with an optical fiber was introduced into the fistula for light delivery. Seven days after the first laser session, it was noted complete resolution of both edema and erythema; after six weeks, the ORN fistula was no longer present. According to the current case, the combination of PBMT and aPDT with an optical fiber to deliver the laser light seems to be a suitable alternative for restricted areas such as fistula paths.


Assuntos
Anti-Infecciosos , Osteorradionecrose , Fotoquimioterapia , Anti-Infecciosos/uso terapêutico , Humanos , Fibras Ópticas , Fístula Bucal/tratamento farmacológico , Osteorradionecrose/tratamento farmacológico , Osteorradionecrose/terapia , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/uso terapêutico , Estudos Retrospectivos
8.
Int J Dent ; 2020: 2494128, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32148500

RESUMO

BACKGROUND: The aim of this study was to assess the volumetric stability and bone formation in grafts with Bio-Oss and autogenous bone at different proportions in rabbit calvaria. Material and Methods. Ten rabbits received four titanium cylinders in their calvaria and randomly divided into the following groups: Group I: Bio-Oss (100%), Group II: Bio-Oss (75%) + autogenous bone (25%), Group III: Bio-Oss (50%) + autogenous bone (50%), and Group IV: autogenous bone (100%). After twelve weeks, the animals were euthanized, and samples were collected for clinical and histological analysis. RESULTS: Clinical analysis showed that Groups I (90.43 ± 8.99) and II (90.87 ± 7.43) had greater dimensional stability compared to Group IV (P=0.0005). Histologically, Groups I, II, and III showed areas of bone formation with particles of biomaterial remaining in close contact with the newly formed bone. However, there were no significant differences between the groups regarding the newly formed bone area. CONCLUSION: It was concluded that the use of Bio-Oss either alone or associated with the autogenous bone at a proportion of 25% showed superior dimensional stability compared to the use of autogenous bone in the proposed experimental model.

9.
J Periodontol ; 91(10): 1295-1306, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32052436

RESUMO

BACKGROUND: Recombinant human bone morphogenetic protein 2 (rhBMP-2) is an osteoinductor frequently used for bone regeneration in oral and maxillofacial surgery. There is no consensus about the ideal carrier for this growth factor. The aim of this study was to compare the bone augmentation, bone microarchitecture, and biodegradation rate of additional carriers to rhBMP-2/absorbable collagen sponge (ACS) in a vertical guided bone regeneration model. METHODS: Four titanium cylinders were fixed onto the calvaria of rabbits (n = 20) that received (n = 10) or not (n = 10) rhBMP-2/ACS in conjunction with one of the carriers: beta-tricalcium phosphate (ß-TCP), biphasic calcium phosphate (BCP), bovine bone mineral (BBM) or blood clot. The samples were analyzed by means of microcomputed tomography and histomorphology after 14 weeks. RESULTS: All the materials with rhBMP-2/ACS exhibited improvement on bone augmentation, mainly BCP (P = 0.033) and ß-TCP (P = 0.038), in the upper portion of the cylinder. Although trabecular anisotropy was improved in all the materials groups, trabecular connectivity was diminished when the biomaterials received rhBMP-2/ACS. Resorption rate of the remaining biomaterial was improved by rhBMP-2/ACS, mainly in BBM (P <0.01) and ß-TCP (P <0.01). BBM exhibited the highest osteoclast density compared with the other materials groups. CONCLUSIONS: BCP and ß-TCP biomaterials exhibited a synergic effect with rhBMP-2/ACS, acting as suitable and viable carriers for vertical bone augmentation. The addition of rhBMP-2 significantly affected the biodegradation of ß-TCP and BBM, accelerating the resorption of these materials.


Assuntos
Substitutos Ósseos , Animais , Proteína Morfogenética Óssea 2 , Proteínas Morfogenéticas Ósseas , Regeneração Óssea , Substitutos Ósseos/uso terapêutico , Bovinos , Colágeno , Humanos , Coelhos , Proteínas Recombinantes , Fator de Crescimento Transformador beta , Microtomografia por Raio-X
10.
Ortho Sci., Orthod. sci. pract ; 13(52): 88-95, 2020. tab, ilus
Artigo em Português | BBO - Odontologia | ID: biblio-1146550

RESUMO

INTRODUÇÃO: Os aparelhos intraorais (AIO) possuem indicação para tratamento da Síndrome da Apneia Obstrutiva do Sono (SAOS) inclusive em pacientes com baixa adesão ao CPAP. A polissonografia com o AIO pode confirmar benefício terapêutico. MÉTODOS: Compararam-se os resultados polissonográficos de um AIO semiflexível em pacientes sob uso inadequado do CPAP por meio de estudo-piloto retrospectivo, incluindo 17 pacientes (11 homens e 6 mulheres) com 53,7 +- 7,8 anos, IMC de 27,5 +- 4,1kg/m2 e índice de apneia- -hipopneia basal (IAH) de 35,0 +- 19,8/h. Confirmados o uso inadequado ou recusa do CPAP, os pacientes receberam um aparelho com propulsão semiflexível (A-QUALITY) e, após titulação completa, novas polissonografias foram comparadas aos registros basais e com CPAP. Utilizou-se ANOVA para medidas repetidas e post-hoc Bonferroni (p < 0,05). RESULTADOS: Houve redução semelhante no IAH com AIO (7,7 +- 1,7/h) e CPAP (6,1 +- 1,6/h), ambos comparados ao basal (p < 0,001). O índice de dessaturação de O2 foi reduzido com AIO (2,4 +- 0,6/h) e CPAP (1,3 +- 0,6/h), ambos comparados ao basal (15,7 +- 3,8), (p <0,001). O índice de despertares também foi minimizado com AIO (7,2 +- 1,9/h) e CPAP (4,2 +- 0,7/h), ambos comparados ao basal (18,9 +- 5,3), (p<0,001). A eficiência do sono foi maior com o AIO comparado ao CPAP (87,2 +- 2,1 x 75,6 +- 3,9) (p<0,05). CONCLUSÃO: O tratamento com o aparelho selecionado resultou em melhora nos registros polissonográficos nessa amostra e pode ser indicado como alternativa ao CPAP em pacientes subtratados (AU)


INTRODUCTION: Intraoral appliances (IOA) are indicated for treatment of Obstructive Sleep Apnea Syndrome (OSAS) even in patients with poor adherence to CPAP. Polysomnography with IOA may confirm therapeutic benefit. METHODS: Polysomnographic results of a semiflexible IOA in patients under inadequate use of CPAP were compared by a retrospective pilot study including 17 patients (11 men and 6 women) aged 53.7 +- 7.8 years, BMI of 27.05 +- 4.1kg/m2 and basal apnea-hypopnea index (AHI) of 35.0 +- 19.8/h. Confirmed the inappropriate use or refusal of CPAP, the patients received a semiflexible propulsion device (AQUALITY) and, after complete titration, new polysomnographies were compared to baseline and CPAP registers. ANOVA was used for repeated and post-hoc Bonferroni measurements (p <0.05). RESULTS: There was a similar reduction in AHI with OA (7.7 +- 1.7/h) and CPAP (6.1 +- 1.6/h), both compared to baseline (p <0.001). The O2 desaturation index was reduced with IOA (2.4 +- 0.6 h) and CPAP (1.3 +- 0.6/h), both compared to baseline (15.7 +- 3.8) (p <0.001). Awakening rates were also minimized with IOA (7.2 +- 1.9/h) and CPAP (4.2 +- 0.7/h), both compared to baseline (18.9 +- 5.3) (p <0.001). Sleep efficiency was higher with IOA compared to CPAP (87,2 +- 2,1 x 75,6 +- 3,9) (p <0.05). CONCLUSION: Treatment with the selected device resulted in improved polysomnographic records in this sample and may be indicated as an alternative to CPAP in undertreated patients. (AU)


Assuntos
Humanos , Desenho de Aparelho Ortodôntico , Polissonografia , Avanço Mandibular , Apneia Obstrutiva do Sono , Pressão Positiva Contínua nas Vias Aéreas
11.
Int J Oral Maxillofac Implants ; 34(1): 159-164, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30695090

RESUMO

PURPOSE: The aim of this retrospective cohort study was to assess the effects of annual maintenance over a 7-year period on the peri-implant health of patients rehabilitated with overdentures using clinical and radiographic parameters. MATERIALS AND METHODS: In order to be considered for inclusion in the study, patients had to have been rehabilitated with overdentures that had at least two implants placed in the mandible and four implants in the maxilla. Patients were divided into two groups: group 1 comprised individuals who had undergone annual maintenance over the previous 7 years, and group 2 comprised those who had not attended any dental appointment over the previous 7 years. All patients were submitted to clinical peri-implant examinations and radiographic assessments. RESULTS: Sixty-six patients received 396 implants of the external hexagon type, 132 in the mandible and 264 in the maxilla. Group 1 (44 patients with 264 implants) had a mean probing depth of 2.72 mm, while group 2 (22 patients with 132 implants) had a mean probing depth of 3.10 mm. It can be concluded that the mean of the variable probing depth is influenced by the presence of bleeding (P = .0005) and the implementation of maintenance (P = .0188), whereas plaque and local variables were not otherwise significant (P = .0605 and .0796, respectively). CONCLUSION: In this study, it was possible to observe better clinical conditions in individuals who had attended annual appointments for maintenance purposes.


Assuntos
Implantes Dentários , Revestimento de Dentadura , Idoso , Prótese Dentária Fixada por Implante/efeitos adversos , Feminino , Humanos , Masculino , Mandíbula , Maxila , Pessoa de Meia-Idade , Estudos Retrospectivos
12.
Braz Dent J ; 29(4): 325-334, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30462757

RESUMO

Several techniques have been proposed for vertical bone regeneration, and many of them use bone autogenous and allogeneic grafts. The purpose of this study was to compare demineralised freeze-dried bone allografts (DFDBA), fresh-frozen (FF) allografts, autogenous bone grafts to find differences between volumetric and histological quantity of bone formation and vertical bone growth dynamic. A vertical tissue regeneration bone model was performed in rabbit calvarias under general anaesthesia. Four hollow cylinders of pure titanium were screwed onto external cortical bone calvarias in eight rabbits. Each one of the cylinders was randomly filled with one intervention: DFDBA, FF, autogenous bone, or left to be filled with blood clot (BC) as control. Allogeneic grafts were obtained from a ninth animal following international standardised protocols for the harvesting, processing, and cryopreservation of allografts. Autogenous graft was obtained from the host femur scraping before adapting hollow cylinders. Animals were euthanized at 13 weeks. Vertical volume was calculated after probe device measurements of the new formed tissue inside the cylinders and after titanium cylinders were removed. Histomorphometry and fluorochrome staining were used to analyse quantity and dynamic of bone formation, respectively. Results showed that DFDBA and fresh-frozen bone improved the velocity and the quantity of bone deposition in distant portions of the basal plane of grafting. Remaining material in allograft groups was more intense than in autogenous group. Both allografts can be indicated as reliable alternatives for volume gain and vertical bone augmentation.


Assuntos
Regeneração Óssea , Transplante Ósseo/métodos , Modelos Biológicos , Animais , Parafusos Ósseos , Corantes Fluorescentes/química , Liofilização , Masculino , Microscopia de Fluorescência , Coelhos , Transplante Autólogo , Transplante Homólogo
13.
Braz. dent. j ; 29(4): 325-334, July-Aug. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-974170

RESUMO

Abstract Several techniques have been proposed for vertical bone regeneration, and many of them use bone autogenous and allogeneic grafts. The purpose of this study was to compare demineralised freeze-dried bone allografts (DFDBA), fresh-frozen (FF) allografts, autogenous bone grafts to find differences between volumetric and histological quantity of bone formation and vertical bone growth dynamic. A vertical tissue regeneration bone model was performed in rabbit calvarias under general anaesthesia. Four hollow cylinders of pure titanium were screwed onto external cortical bone calvarias in eight rabbits. Each one of the cylinders was randomly filled with one intervention: DFDBA, FF, autogenous bone, or left to be filled with blood clot (BC) as control. Allogeneic grafts were obtained from a ninth animal following international standardised protocols for the harvesting, processing, and cryopreservation of allografts. Autogenous graft was obtained from the host femur scraping before adapting hollow cylinders. Animals were euthanized at 13 weeks. Vertical volume was calculated after probe device measurements of the new formed tissue inside the cylinders and after titanium cylinders were removed. Histomorphometry and fluorochrome staining were used to analyse quantity and dynamic of bone formation, respectively. Results showed that DFDBA and fresh-frozen bone improved the velocity and the quantity of bone deposition in distant portions of the basal plane of grafting. Remaining material in allograft groups was more intense than in autogenous group. Both allografts can be indicated as reliable alternatives for volume gain and vertical bone augmentation.


Resumo Várias técnicas foram propostas para regeneração óssea vertical, e muitas delas usam enxertos ósseos e alogênicos ósseos. O objetivo deste estudo foi comparar os aloenxertos ósseos congelados desmineralizados (DFDBA), os aloenxertos congelados frescos (FF) com os enxertos ósseos autógenos para encontrar diferenças entre o volume, a histologia da formação óssea e a dinâmica do crescimento ósseo vertical. Um modelo ósseo de regeneração tecidual vertical foi realizado em calvarias de coelho sob anestesia geral. Quatro cilindros ocos de titânio puro foram parafusados nas calvarias de osso cortical externo em oito coelhos. Cada um dos cilindros foi preenchido aleatoriamente com uma intervenção: DFDBA, FF, osso autógeno ou com coágulo sanguíneo (BC) como controle. Os enxertos alogênicos foram obtidos a partir de um nono animal seguindo protocolos internacionais padronizados para a coleta, processamento e criopreservação de aloenxertos. O enxerto autógeno foi obtido da raspagem do fêmur do hospedeiro antes de adaptar os cilindros ocos. Os animais foram eutanasiados após 13 semanas. O volume vertical foi calculado após a medição, por meio de sonda milimetrada, do novo tecido formado dentro dos cilindros e após a remoção dos cilindros de titânio. Histomorfometria e coloração com fluorocromios foram utilizados para analisar a quantidade e a dinâmica da formação óssea. Os resultados mostraram que DFDBA e osso fresco congelado melhoraram a velocidade e a quantidade de deposição óssea em porções distantes do plano basal de enxerto. O material remanescente nos grupos de aloenxerto foi mais intenso do que em grupo autógeno. Ambos os aloenxertos podem ser indicados como alternativas confiáveis para ganho de volume e aumento ósseo vertical.


Assuntos
Animais , Masculino , Coelhos , Regeneração Óssea , Transplante Ósseo/métodos , Modelos Biológicos , Transplante Autólogo , Transplante Homólogo , Parafusos Ósseos , Corantes Fluorescentes/química , Liofilização , Microscopia de Fluorescência
14.
ImplantNewsPerio ; 3(4): 683-693, jul.-ago. 2018. ilus
Artigo em Português | BBO - Odontologia | ID: biblio-911442

RESUMO

O ameloblastoma é um tumor odontogênico benigno, localmente invasivo, capaz de infiltrar-se pelos espaços medulares do osso e, quando em estágio inicial, geralmente não apresenta indícios radiográficos ou macroscópicos. Muitas vezes, pacientes submetidos a tratamento ressectivo perdem grande parte da maxila ou mandíbula, necessitando de uma alternativa de tratamento para restabelecer a função e a estética. O objetivo deste relato de caso foi apresentar um acompanhamento de quatro anos de uma reabilitação com implantes zigomáticos em paciente submetido à ressecção de maxila anterior devido a um tumor odontogênico do tipo ameloblastoma. Quatro meses após a realização da cirurgia de ressecção do ameloblastoma na região anterior de maxila, foram instalados dois implantes com ancoragem zigomática no lado esquerdo, um implante com ancoragem zigomática no lado direito e dois implantes regulares hexágono externo no lado direito. Em seguida, foi feita uma prótese provisória imediata. Seis meses depois, os implantes foram carregados com a prótese final em resina acrílica. Após quatro anos de acompanhamento, não foram observados sintomas dolorosos, inflamação ou infecção peri-implantar, instabilidade do implante ou reabsorção óssea. No presente caso, a reabilitação da maxila atrófica com implantes no osso zigomático proporcionou bons resultados funcionais e estéticos a longo prazo. Assim, o uso de implantes zigomáticos associados a implantes padrão oferece vantagens na reabilitação de maxilares severamente reabsorvidos, principalmente quando a indicação é feita corretamente e com o conhecimento da técnica cirúrgica. (AU)


Ameloblastoma is a benign, locally invasive odontogenic tumor capable of infiltrating the bone marrow spaces, and when at the initial stage, it generally does not show radiographic or macroscopic evidence. Patients undergoing resection treatment lose a large part of the maxilla or mandible, requiring an alternative treatment to re-establish the function and aesthetics. The objective of this case report was to present a 4-years follow-up of a rehabilitation with zygomatic implants in a patient submitted to anterior maxillary resection due to an odontogenic tumor of the ameloblastoma type. After 4 months of the ameloblastoma resection surgery in the anterior maxillary region, 2 implants were placed with zygomatic anchoring on the left side, 1 implant with zygomatic anchoring on the right side and 2 regular external hexagon implants placed on the right side and then it was done an immediate provisional prosthesis. Six months later, the implants were loaded with the fi nal acrylic resin prosthesis. After 4-years of follow-up no painful symptoms, inflammation or peri-implant infection, implant instability or bone resorption were observed. In the present case, the atrophic maxilla rehabilitation with implants in the zygomatic bone provided long-term functional and aesthetic results. Thus, the zygomatic implants associated with standard implants offers advantages in severely reabsorbed maxillae rehabilitation, especially when the indication is made correctly and also with the knowledge of the surgical technique. (AU)


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Ameloblastoma , Tumores Odontogênicos , Implantes Dentários , Implantação Dentária Endóssea , Estética Dentária
15.
Dental Press J Orthod ; 23(1): 79-86, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29791688

RESUMO

INTRODUCTION: The surgically assisted rapid maxillary expansion is a procedure that reduces the resistance of the sutures correcting the posterior crossbite in adults. OBJECTIVE: The aim of this study was to evaluate the periodontal status of 17 adults submitted to this procedure. METHODS: The clinical attachment level (CAL), gingival recession, attached gingiva and bleeding were evaluated in maxillary first premolars and molars, central and lateral incisors of right and left sides before surgery, 5 days and 6 months after. Means, standard deviation, medians, minimum and maximum values were compared among the evaluations using the Friedman and McNemar tests. RESULTS: There was a statistically significant increase in CAL in the right central incisor, right and left premolars and right and left molars. There was a statistically significant increase in gingival recession in the right and left premolars and molars. The amount of attached gingiva significantly decreased in right premolars and right and left molars. There was increase in bleeding in most of the teeth. CONCLUSION: Results indicated that the surgically assisted rapid maxillary expansion might cause alterations in periodontal tissue.


Assuntos
Retração Gengival/etiologia , Maxila/cirurgia , Técnica de Expansão Palatina/efeitos adversos , Perda da Inserção Periodontal/etiologia , Adulto , Feminino , Hemorragia/etiologia , Humanos , Masculino , Pessoa de Meia-Idade , Técnica de Expansão Palatina/instrumentação
16.
Int J Oral Maxillofac Implants ; 33(3): 512­522, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29543927

RESUMO

PURPOSE: The objective of this investigation was to assess vertical bone augmentation using deproteinized bovine bone mineral (DBBM) infused or not with recombinant human bone morphogenetic protein (rhBMP-2) in rabbit tibiae. MATERIALS AND METHODS: A total of 18 female rabbits (New Zealand) received two blocks of DBBM in each tibia. The DBBM blocks were randomly assigned into four experimental groups: DBBM (only the bone graft); DBBM associated with absorbable collagen sponge (ACS); DBBM plus rhBMP-2 (1.5 mg/mL); and DBBM infused with rhBMP-2 (1.5 mg/mL) in an ACS carrier. Animals were sacrificed after 12 weeks, and the tibiae containing the DBBM blocks were dissected and analyzed radiographically (microcomputed tomography [micro-CT]), histologically, and immunohistochemically. RESULTS: Micro-CT analysis showed a considerable increase in bone volume (BV) and BV/tissue volume in the rhBMP-2/ACS group compared with all the others. Trabeculae thickness also increased in the rhBMP-2/ACS group compared with the DBBM/ACS group. Trabecular number, separation, and bone mineral density were not different among groups. Histomorphometric evaluation showed increased newly formed bone in the rhBMP-2/ACS group compared with the DBBM and DBBM/ACS groups. The amount of residual bone graft was statistically higher in the rhBMP-2 groups compared with the DBBM/ACS group. Immunohistochemical analysis showed that the vascular endothelial growth factor (VEGF) expression was more intense in the rhBMP-2/ACS group compared with the DBBM/ACS group. The immunopositivity for type 1 collagen tended to be higher in the two groups with rhBMP-2. CONCLUSION: Collectively, the results of this study suggest that the addition of rhBMP-2 in an ACS carrier placed on top of the DBBM graft enhanced bone formation in this animal model.


Assuntos
Implantes Absorvíveis , Aumento do Rebordo Alveolar/métodos , Proteína Morfogenética Óssea 2/farmacologia , Regeneração Óssea/efeitos dos fármacos , Transplante Ósseo/métodos , Colágeno/farmacologia , Minerais/farmacologia , Fator de Crescimento Transformador beta/farmacologia , Animais , Produtos Biológicos/farmacologia , Densidade Óssea , Proteína Morfogenética Óssea 2/uso terapêutico , Bovinos , Colágeno/administração & dosagem , Modelos Animais de Doenças , Feminino , Coelhos , Proteínas Recombinantes/farmacologia , Proteínas Recombinantes/uso terapêutico , Tíbia/metabolismo , Tíbia/patologia , Tíbia/cirurgia , Fator de Crescimento Transformador beta/uso terapêutico , Fator A de Crescimento do Endotélio Vascular/metabolismo , Microtomografia por Raio-X
17.
Dental press j. orthod. (Impr.) ; 23(1): 79-86, Jan.-Feb. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-891120

RESUMO

ABSTRACT Introduction: The surgically assisted rapid maxillary expansion is a procedure that reduces the resistance of the sutures correcting the posterior crossbite in adults. Objective: The aim of this study was to evaluate the periodontal status of 17 adults submitted to this procedure. Methods: The clinical attachment level (CAL), gingival recession, attached gingiva and bleeding were evaluated in maxillary first premolars and molars, central and lateral incisors of right and left sides before surgery, 5 days and 6 months after. Means, standard deviation, medians, minimum and maximum values were compared among the evaluations using the Friedman and McNemar tests. Results: There was a statistically significant increase in CAL in the right central incisor, right and left premolars and right and left molars. There was a statistically significant increase in gingival recession in the right and left premolars and molars. The amount of attached gingiva significantly decreased in right premolars and right and left molars. There was increase in bleeding in most of the teeth. Conclusion: Results indicated that the surgically assisted rapid maxillary expansion might cause alterations in periodontal tissue.


RESUMO Introdução: a expansão rápida da maxila assistida cirurgicamente (ERMAC) é um procedimento que reduz a resistência das suturas, corrigindo a mordida cruzada posterior em adultos. Objetivo: o objetivo deste estudo foi avaliar o status periodontal de 17 adultos submetidos a esse procedimento. Métodos: o nível clínico de inserção (NCI), a recessão gengival, gengiva inserida e sangramento foram avaliados nos primeiros pré-molares, molares, incisivos centrais e laterais superiores dos lados direito e esquerdo antes da cirurgia, e depois de 5 dias e 6 meses. Médias, desvios-padrão, medianas, valores mínimos e máximos foram comparados entre as avaliações, usando os testes de Friedman e McNemar. Resultados: houve aumento estatisticamente significativo no NCI no incisivo central direito, pré-molares direito e esquerdo e molares direito e esquerdo. Houve aumento estatisticamente significativo na recessão gengival nos pré-molares e nos molares direito e esquerdo. A quantidade de gengiva inserida diminuiu significativamente nos pré-molares direitos e molares direitos e esquerdos. Houve aumento no sangramento na maioria dos dentes. Conclusão: os resultados indicaram que a ERMAC pode causar alterações no tecido periodontal.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Técnica de Expansão Palatina/efeitos adversos , Perda da Inserção Periodontal/etiologia , Retração Gengival/etiologia , Maxila/cirurgia , Técnica de Expansão Palatina/instrumentação , Hemorragia/etiologia
18.
J Craniomaxillofac Surg ; 46(1): 142-147, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29198577

RESUMO

OBJECTIVE: This study compared stability, removal torque, bone implant contact (BIC) and area (BA) of implants installed simultaneously with onlay autografts or allografts in rabbits' tibias. MATERIAL AND METHODS: Total of 18 rabbits were used in this study. Fresh frozen allografts were obtained from six animals at T(-6). Two implants with autogenous grafts (Group 1) or allografts (Group 2) were simultaneously inserted into both sides of the tibiae in a vertical periimplant defect model at T0. The resonance frequency (ISQ) was measured in implant proximal epiphysis on the day of installation of T0 and T18 (18 weeks post-surgery). At T18 the removal torque was assessed at the distal implants, the implants' proximal epiphysis and surrounding bone were harvested to perform histomorphometric analysis. The BIC and BA within the limits of the implants threads were evaluated. RESULTS: The ISQ revealed a statistically significant difference between T0 and T18 in each group (p = 0.024, p = 0.003). The removal torque indicates that there was no significant difference between the two groups (p = 0.47). No significant differences were observed between the groups regarding both BIC (p = 0.3713) and the BA (p = 0.3883). CONCLUSION: Both grafts and implants demonstrated the same stability, torque removal and the BIC and BA.


Assuntos
Transplante Ósseo , Implantação Dentária Endóssea , Aloenxertos , Animais , Autoenxertos , Coelhos , Tíbia
19.
ImplantNewsPerio ; 2(6): 1042-1048, nov.-dez. 2017. tab
Artigo em Português | LILACS, BBO - Odontologia | ID: biblio-880491

RESUMO

Objetivo: comparar as técnicas de lateralização (LNAI) e transposição do nervo alveolar inferior (TNAI) com a taxa de disfunção neurossensorial, bem como a taxa de sucesso dos implantes dentários. Material e métodos: uma pesquisa foi realizada no período de 1987 a 2016, no banco de dados Medline/PubMed, com as palavras-chave "implantes dentários", "nervo alveolar inferior", "lateralização", "transposição", "neurossensorial" e "taxa de sucesso". Foram incluídos artigos retrospectivos e prospectivos em seres humanos, e que apresentassem relatos de disfunção neurossensorial e taxa de sucesso dos implantes dentários na região posterior da mandíbula, após procedimentos de lateralização ou transposição do nervo alveolar. Resultados: dos 142 artigos encontrados na primeira fase de seleção, apenas 26 foram incluídos na técnica LNAI, com um total de 524 procedimentos, sendo 228 na técnica de TNAI e 296 na LNAI, que foram incluídos neste estudo. O número de implantes instalados pela técnica de TNAI foi de 625, e pela técnica de LNAI foi de 401. As técnicas de TNAI apresentaram um índice inicial maior de disfunção neurossensorial, quando comparadas à técnica de LNAI. A taxa de sucesso dos implantes para a té cnica de TNAI ficou entre 80% e 100%, e para a té cnica de LNAI fi cou entre 90,5% e 100%. Conclusão: a LNAI vem sendo uma boa indicação para a reabilitação de mandíbulas atróficas verticalmente, e sua execução com o piezo diminui o risco de distúrbio sensorial. As altas taxas de sucesso dos implantes podem ser atribuídas à possibilidade da instalação de implantes longos com ancoragem bicortical, favorecendo a estabilidade primária e a biomecânica.


Objective: to compare lateralization techniques (LNAI) and transposition of the inferior alveolar nerve (TNAI) with the rate of sensorineural dysfunction, as well as the success rate of dental implants. Material and methods: a survey was carried out between 1987 and 2016 in the Medline/PubMed database, with the key words "dental implants", "inferior alveolar nerve", "lateralization", "transposition", "neurosensorial", "success rate". Retrospective and prospective articles in humans that presented reports of sensorineural dysfunction and success rate of dental implants in the posterior region of the mandible after procedures of lateralization or transposition of the alveolar nerve were included. Results: in the fi rst phase of the selection, 142 articles were retrieved, but only 26 articles on LNAI, with a total of 524 procedures, 228 on TNAI technique and 296 the LNAI, were included in the study. The number of implants installed by the TNAI technique was 625 and by the LNAI 401. The TNAI present a higher initial index of sensorineural dysfunction than the LNAI and the success rate of the implants was for the TNAI between 80% to 100%, and for the LNAI between 90.5% and 100%. Conclusion: LNAI has been a good indication for the rehabilitation of atrophic mandibles vertically and its execution with piezo reduces the risk of sensory disturbance. The high success rates of implants can be attributed to the possibility of installing long implants with bicortical anchoring favoring primary stability and biomechanics.


Assuntos
Humanos , Masculino , Feminino , Implantação Dentária , Perda Auditiva Neurossensorial , Nervo Mandibular/cirurgia , Procedimentos Cirúrgicos Pré-Protéticos Bucais , Osteotomia , Transtornos das Sensações , Fenômenos Biomecânicos
20.
Int. arch. otorhinolaryngol. (Impr.) ; 21(2): 126-133, Apr.-June 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-892799

RESUMO

Abstract Introduction Maxillary sinus disease is common and numerous disorders can affect this anatomical area. Abnormalities can be classified as: non-neoplastic, neoplastic benign, and neoplastic malignant. Objective Evaluate through CT the prevalence of diseases in maxillary sinuses, using the Radiology Department's database of a hospital in São Paulo city. Methods The sample consisted of 762 facial CT scans that we divided into three groups: Group A (12-19 years old); Group B (20-49 years old); Group C (above 50 years old); and male or female. We considered the following pathological processes: I - Mucoperiosteal Thickening; II - Chronic Sinusitis; III - Chronic Odontogenic Sinusitis; IV - Rhinosinusitis; V - Polypoid Lesions; VI - Bone Lesions; VII - Neoplasms; VIII - Antrolith; IX - Foreign Bodies; X - Oroantral Fistula. Results Our study found that 305 exams (40.02%) were normal and 457 exams (59.97%) were abnormal. We found the following disease frequencies: focal mucoperiosteal thickening (21.25%); polypoid lesions (10.76%); chronic sinusitis (7.48%); chronic odontogenic sinusitis (2.29%); neoplasms (2.03%); rhinosinusitis (1.77%); bone lesions, foreign bodies and oroantral fistula in 0.65%; 0.13% and 0.06% respectively. There was no significant difference between male and female, and Groups A, B, or C when relating the frequencies of abnormalities found. There was no significant difference between male and female and the age group for the side of the altered maxillary sinus. Conclusion We observed a high prevalence of sinus maxillary diseases. Mucoperiosteal thickening; acute, chronic, and odontogenic sinusitis; polypoid lesions and neoplasms have high prevalence in maxillary sinuses. Thus, facial CT exam was effective for the evaluation of diseases in maxillary sinuses.

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